Creatine Supplements: Boost Your Strength and Power

Unveil the Incredible Transformative Benefits of Premium Creatine Supplements for Enhancing Your Strength

In the realm of strength training, creatine has emerged as a fundamental supplement recognised for its remarkable efficacy. Supported by a wealth of scientific studies, this powerful compound is celebrated for its ability to significantly enhance your strength training performance. The multitude of advantages provided by premium creatine supplements for strength has rendered them essential for both elite athletes and those embarking on their fitness journey. By exploring these benefits in depth, you can arm yourself with the information necessary to make informed decisions that will not only elevate your training routine but also optimise your overall performance.

Unlock Unprecedented Muscle Growth by Incorporating Effective Creatine Supplementation

The primary appeal of creatine lies in its extraordinary capability to dramatically enhance muscle growth. Numerous research studies have consistently shown that creatine plays a pivotal role in boosting protein synthesis, a crucial process for increasing muscle mass. This is especially important for individuals dedicated to strength training, as a rise in muscle mass directly correlates with substantial strength improvements.

By integrating creatine into your training regime, you elevate the levels of phosphocreatine within your muscle fibres, a necessary compound that aids in the production of adenosine triphosphate (ATP), the body’s primary energy source for various cellular functions. Elevated ATP levels facilitate more intense workouts, allowing you to lift heavier weights or perform additional repetitions. As you consistently challenge your muscles with increased loads, they adapt by growing larger and stronger.

Additionally, creatine plays a vital role in promoting cellular hydration. By drawing water into muscle cells, it enhances their volume, giving them a fuller appearance and creating an anabolic environment conducive to growth. This “swell” effect not only enhances physical aesthetics but also boosts your workout performance, enabling you to endure and thrive in more demanding training sessions.

The advantages of muscle growth extend beyond your time at the gym. Increased muscle mass is often associated with a heightened metabolic rate, which can aid in fat loss—an additional benefit for those seeking to refine their body composition. Whether you’re a professional athlete or a recreational lifter, the muscle growth benefits associated with premium creatine supplements for strength can greatly accelerate your progress towards achieving your fitness aspirations.

Supercharge Your Workout Performance with the Power of Creatine

Imagine stepping into the gym filled with an unshakeable sense of invincibility, powering through your workout with unmatched intensity and energy. This isn’t mere fantasy; it’s a reality for those who incorporate creatine into their training regimens. By replenishing ATP reserves, creatine supplementation empowers you to undertake more rigorous workouts, leading to enhanced performance in strength training.

Research reveals that creatine can improve performance in high-intensity exercises by an impressive 10-20%. This enhancement is particularly pronounced during explosive movements—such as sprinting, jumping, or lifting heavy weights—where you can exert greater force and power. This increase in output translates to a higher training volume over time, which is essential for developing strength effectively.

Athletes across a variety of sports disciplines, including weightlifting and sprinting, have harnessed the transformative power of creatine to elevate their performance levels. For instance, sprinters frequently report enhanced speed when incorporating creatine, enabling them to achieve personal bests in competitive settings. Similarly, strength athletes often note their increased capacity to lift heavier weights, which directly correlates with greater muscle growth and overall strength gains.

The essential takeaway is that premium creatine supplements for strength can be revolutionary, enabling you to train with greater intensity and for extended periods. By optimising your performance, you will not only see tangible improvements in your lifts but also experience an uplift in motivation and self-confidence.

Accelerate Your Recovery Times with Strategic Creatine Supplementation

While recovery is frequently overlooked in the realm of strength training, it is just as crucial as the workouts themselves. Creatine supplementation possesses a remarkable ability to significantly reduce muscle cell damage and inflammation, consequently promoting quicker recovery between strength training sessions. This attribute is essential for anyone aiming to maintain a consistent workout schedule.

A notable physiological mechanism at play is creatine’s capacity to lower markers of muscle damage, such as creatine kinase levels, following periods of intense physical exertion. This means that your muscles will experience reduced soreness and fatigue, allowing for a faster return to training. As a result, you can maintain higher training frequencies, which is vital for maximising strength gains.

Additionally, creatine is linked to diminished oxidative stress and inflammation levels in the body. For athletes who engage in rigorous training regimens, cumulative physical stress can lead to overtraining and potential injuries. By incorporating creatine into your supplement routine, you can mitigate these risks, ensuring your body remains primed for peak performance.

This advantage of creatine is particularly beneficial for strength athletes who often train multiple times per week. With shorter recovery times, you can optimise your workouts and consistently challenge your strength levels without enduring the lengthy downtime typically associated with intense training sessions.

Amplify Your Power Output with the Benefits of Creatine

The ability to generate explosive power is a vital aspect of effective strength training. Creatine supplementation can significantly enhance short-term power output, rendering it an invaluable asset for athletes. This advantage is especially relevant for sports that demand quick bursts of energy, such as Olympic weightlifting or sprinting events.

By elevating the levels of phosphocreatine in your muscles, creatine facilitates the rapid regeneration of ATP, which is crucial for muscle contractions. This enables you to execute more explosive movements, which is essential for enhancing your overall power. Research indicates that athletes who utilise creatine achieve greater peak power outputs during testing conditions compared to those who refrain from using it.

Moreover, the benefits of increased power output extend beyond merely lifting weights. Athletes participating in team sports, such as basketball or football, can experience improvements in their speed, jumping capabilities, and agility when executing directional changes. This enhanced performance translates into superior results in competitions, whether on the field, court, or track.

By incorporating premium creatine supplements for strength into your training regimen, you can elevate your workouts to extraordinary heights. The enhancement in power output enables you to train harder, ultimately resulting in significant improvements in both strength and athletic performance.

Enhance Hydration for Optimal Performance with Creatine Supplementation

Proper hydration is paramount for peak athletic performance, and creatine offers a unique advantage in this area. By supplementing with creatine, you increase intracellular water content, which can lead to enhanced muscle function and endurance during strength training. Well-hydrated muscles operate more efficiently, resulting in more effective workout sessions.

Creatine draws water into muscle cells, increasing their volume and creating an optimal environment for effective muscle contractions. This hydration effect not only amplifies performance during workouts but also aids in nutrient transport, ensuring that your muscles receive the essential components necessary for recovery and growth.

In an environment where athletes frequently neglect hydration, creatine provides a dual advantage. It not only sustains muscle hydration but also assists in preventing dehydration during intense training sessions. Maintaining appropriate hydration levels can significantly reduce the risk of muscle cramps and fatigue, enabling you to maximise your training intensity.

For those engaged in endurance activities or high-intensity interval training, the hydration benefits of creatine can be transformative. By maintaining optimal hydration levels, you can uphold your performance over extended durations, ultimately leading to enhanced strength gains.

Investigate the Leading Brands of Creatine Supplements for Optimal Performance

With a vast selection of creatine products available on the market, navigating through the options can be overwhelming, particularly when searching for the most effective choices. Here, we highlight some of the premium creatine supplements for strength that are favoured by athletes and fitness enthusiasts alike due to their proven quality and effectiveness.

Brand A: Setting the Standard for Creatine Monohydrate Excellence

Renowned for its premium creatine monohydrate, Brand A has cultivated a loyal following among strength athletes. This brand prioritises purity and effectiveness, making it a leading choice for dedicated trainers.

What distinguishes Brand A is its unwavering commitment to quality assurance. Each batch undergoes rigorous testing to ensure compliance with the highest industry standards. This level of transparency fosters trust among consumers, allowing athletes to feel confident that they are using a supplement that is both safe and effective.

The creatine monohydrate provided by Brand A is micronised, enhancing its solubility and absorption within the body. This means you will experience the benefits of increased strength and muscle growth more swiftly than with other creatine forms. Whether you are performing heavy lifts or engaging in high-intensity training, Brand A’s creatine can assist you in achieving peak performance.

With an outstanding reputation within the fitness community and numerous positive testimonials, Brand A stands out as a premier option for anyone looking to incorporate creatine into their strength training programme.

Brand B: Versatile Creatine Formulations Tailored to Meet Every Athlete’s Needs

Brand B offers a diverse array of creatine formulations, including HCL and Kre-Alkalyn, designed to cater to various requirements in strength training. This versatility has made it a favourite among individuals with specific preferences or digestive concerns regarding conventional creatine monohydrate.

One of Brand B’s standout products is its creatine HCL, which boasts superior solubility and absorption rates compared to other forms. This makes it an excellent option for those who may experience gastrointestinal discomfort with standard creatine monohydrate. The HCL formulation is engineered to deliver the same benefits of muscle growth and performance enhancement without the common side effects.

Furthermore, Brand B’s Kre-Alkalyn provides a buffered alternative that aims to minimise the conversion of creatine to creatinine, which can reduce its effectiveness for muscle utilisation. For those sensitive to the effects of creatine, these options present valuable alternatives that do not compromise efficacy.

With a strong focus on innovation and quality, Brand B has established itself as a reputable name in the supplement industry. Whether you are a novice or a seasoned athlete, exploring Brand B’s offerings can lead to significant enhancements in your strength training routine.

Brand C: Affordable Quality for Budget-Conscious Athletes Seeking Results

For those mindful of their budget, Brand C presents a cost-effective option that does not compromise on quality. Known for its well-regarded creatine supplement, this brand has carved out a niche in the competitive supplement market.

Despite being more affordable, Brand C’s creatine has garnered praise for its efficacy in promoting strength and muscle growth. Many users report noticeable improvements in their lifting capabilities and overall performance, making it an excellent choice for anyone looking to incorporate creatine into their regimen without overspending.

Brand C also emphasises transparency and customer satisfaction, providing comprehensive product information and responsive customer support. This commitment resonates with athletes seeking a reliable and affordable supplement to enhance their strength training.

In an industry where premium prices often accompany high quality, Brand C challenges the notion that achieving your fitness goals must come at a steep cost. With effective formulations and positive customer feedback, Brand C is a valuable contender among the premium creatine supplements for strength.

Explore the Varied Types of Creatine for Optimal Strength Gains

Understanding the different types of creatine available can greatly influence your supplementation decisions. Each form of creatine offers unique benefits, and knowing which one to select can enhance your strength training experience.

Creatine Monohydrate: The Classic and Proven Choice

Creatine monohydrate remains the most extensively researched and widely used form of creatine, celebrated for its effectiveness in boosting strength and muscle mass. This form consists of creatine combined with a water molecule, making it readily usable by the body.

Countless studies have highlighted the benefits of creatine monohydrate, showcasing its ability to enhance strength, increase lean muscle mass, and improve exercise performance. For strength athletes, this translates into the capacity to lift heavier weights and execute additional repetitions, ultimately leading to significant strength gains over time.

One of the advantages of creatine monohydrate is its affordability and widespread availability. It can be found in nearly every supplement store and is often the first recommendation for newcomers exploring creatine supplementation. Additionally, its well-established safety and efficacy record make it a trusted choice for athletes across various sports disciplines.

While some users may experience temporary weight gain due to water retention, this is often viewed positively, as it indicates muscle hydration, which is vital for optimal performance. Creatine monohydrate continues to be a staple in the supplementation landscape, especially for anyone focused on maximising their strength.

Creatine HCL: The Highly Soluble Alternative

Creatine HCL, or creatine hydrochloride, is rapidly gaining popularity as a more soluble alternative to creatine monohydrate. Its superior solubility means it dissolves more easily in liquids, promoting better digestion and absorption. This characteristic can be especially advantageous for individuals who may experience gastrointestinal discomfort with traditional creatine forms.

Research supports that creatine HCL can be equally effective in boosting strength and athletic performance. Athletes may find they can achieve comparable increases in muscle mass and power output without the bloating often associated with creatine monohydrate, making it an appealing choice for those prioritising comfort in their supplementation routine.

Moreover, due to its unique formulation, creatine HCL often requires a smaller dose to achieve similar effects as creatine monohydrate. This means you need less product to experience the benefits, making it a potentially cost-effective option over time.

For athletes striving to optimise their strength training while minimising gastrointestinal issues, creatine HCL is a worthy alternative. Its distinctive characteristics can contribute to a more enjoyable and effective supplementation experience.

Buffered Creatine: The Gentle Solution for Sensitive Users

Buffered creatine is designed to minimise the conversion of creatine to creatinine, an inactive byproduct that does not aid in muscle performance. This formulation aims to support strength gains without causing the digestive discomfort that some users experience with traditional creatine products.

The buffering process allows buffered creatine to maintain its effectiveness for extended periods within the digestive tract, potentially enhancing absorption and utilisation. Many athletes report fewer side effects and a smoother experience when using buffered creatine, making it a popular choice for those sensitive to conventional forms.

Additionally, buffered creatine often claims to be more effective at lower dosages compared to creatine monohydrate. This can be an attractive option for individuals who aim to avoid high dosages while still reaping the benefits of creatine supplementation.

However, while buffered creatine offers certain advantages, ongoing research regarding its long-term efficacy compared to other forms is still necessary. Athletes should evaluate their personal needs and reactions when considering whether to include buffered creatine in their strength training regimen.

Choosing the right type of creatine can significantly impact your strength training journey. Understanding the distinctions among each form empowers you to make an informed decision that aligns with your goals and preferences.

Your Comprehensive Guide to Selecting the Optimal Creatine Supplement

Choosing the right creatine supplement is crucial for maximising its benefits in strength training. With a plethora of options available, it’s essential to consider various factors to ensure you make the most suitable choice for your health and fitness objectives.

Prioritise Purity and Quality When Selecting Your Creatine

One of the most critical considerations when choosing a creatine supplement is ensuring its purity and quality. Opt for products that undergo third-party testing to confirm you are consuming a supplement free from contaminants and fillers. This is particularly vital for athletes committed to their health and performance.

The label should clearly state the percentage of creatine per serving, as some brands may dilute their products with cheaper ingredients. High-quality creatine monohydrate is often regarded as the gold standard, but other formulations can also offer benefits if they adhere to stringent quality standards.

Conducting thorough research on brands and reading customer reviews can provide valuable insights into product effectiveness and purity. Seek certifications from reputable organisations that indicate the supplement has undergone safety and efficacy testing.

Transparency in labelling is also essential. The best brands clearly outline their ingredients, sourcing, and manufacturing processes, allowing consumers to feel confident in their purchases. By prioritising purity and quality, you set yourself up for success in your strength training endeavours.

Evaluate Form and Absorption for Optimal Results

Consider the form of creatine that best suits your digestion and absorption needs. While creatine monohydrate remains the most popular and thoroughly researched option, alternatives such as creatine HCL or buffered creatine may be more suitable for individuals with sensitive stomachs.

Absorption rates can differ among various types of creatine. For instance, creatine HCL is typically recognised for its superior solubility, leading to quicker absorption. Individuals who experience digestive challenges may find that these alternatives result in fewer gastrointestinal issues.

Trial and error may be necessary to determine which form works best for you. Many athletes start with creatine monohydrate due to its proven effectiveness, then explore other forms if they encounter discomfort. Your choice should align with your specific needs and responses to each formulation.

Experimenting with various forms can also provide valuable insights into which supplement enables you to achieve optimal strength gains. Ultimately, the aim is to select a creatine option that complements your training plan and supports your strength aspirations.

Assess Pricing and Value When Choosing Your Creatine

In the supplement realm, price and value often go hand in hand. While it may be tempting to opt for the cheapest option available, it is critical to balance cost with effectiveness. High-quality creatine may come with a higher price tag, but the benefits it offers can justify the investment.

Consider the cost per serving and the total quantity of creatine in each container. Some brands may appear cheaper initially but provide fewer servings. Evaluating long-term value is essential to ensure you’re receiving an effective product for your strength training.

Don’t overlook discounts or bulk purchasing options, which can make premium creatine more budget-friendly. Many reputable brands offer sales or loyalty programmes to reward their regular customers.

Ensure the product you select fits within your budget while delivering the strength gains you desire. Remember, the effectiveness of a creatine supplement can significantly influence your training outcomes, so investing in quality can yield superior results over time.

Understanding the Optimal Dosage and Timing for Achieving Strength Gains

Grasping the correct dosage and timing for creatine supplementation can heighten its effectiveness and ensure maximum strength gains. Below, we outline best practices for seamlessly incorporating creatine into your training routine.

Loading Phase: Rapidly Saturate Your Muscle Creatine Levels

The loading phase is a widely adopted strategy for quickly saturating your muscles with creatine. During this initial phase, a higher dose is typically administered for a brief period, generally around 20 grams per day, divided into four equal servings. This method guarantees that your muscles become rapidly saturated with creatine, leading to more immediate strength enhancements.

Research indicates that the loading phase can yield significant increases in muscle creatine stores within just one week. For athletes eager to maximise strength gains swiftly, this method can deliver substantial benefits.

However, not everyone finds the loading phase necessary. Some individuals prefer to begin directly with a maintenance dose of around 3-5 grams per day. The loading phase may result in temporary weight gain due to water retention, which could be a concern for individuals focused on remaining within a specific weight class.

Ultimately, whether to engage in a loading phase depends on your personal goals and timeline. Testing both approaches can help you determine which method delivers the most effective results for your strength training.

Maintenance Phase: Sustaining Optimal Creatine Levels

After completing the loading phase, transitioning to a maintenance phase is essential for sustaining creatine levels in your muscles. During this phase, the recommended dosage typically decreases to about 3-5 grams per day. This reduced intake is sufficient to maintain elevated creatine levels, ensuring ongoing strength gains without the need for excessive dosages.

Consistency in daily intake is crucial during this phase. Studies have shown that regular consumption of creatine supports continuous improvements in strength and performance. Skipping days or neglecting to take your dose can result in decreased creatine levels and diminished benefits.

Some athletes opt to cycle on and off creatine, but maintaining regular intake may eliminate the need for cycling. Establishing a consistent routine can help you maximise the advantages of premium creatine supplements for strength throughout your training cycle.

Finding a method that seamlessly integrates into your daily life can enhance adherence. Whether this involves setting reminders or incorporating it into your pre- or post-workout nutrition, consistency remains paramount for optimal results.

Optimal Timing for Creatine Supplementation Around Workouts

Timing your creatine intake can further amplify its positive effects on strength and recovery. There is ongoing debate about whether taking creatine before or after workouts yields superior results; however, research suggests that post-workout consumption may offer greater advantages.

After a workout, your muscles are primed for nutrient absorption. Consuming creatine alongside a post-workout meal or shake can enhance its uptake and facilitate recovery. Pairing creatine with carbohydrates can boost its transport into muscle cells, maximising its overall effectiveness.

For those who prefer to take creatine before workouts, doing so can still provide performance benefits. The key is to establish a routine that aligns with your preferences while ensuring consistent consumption.

Ultimately, the timing of creatine supplementation should complement your routine and personal preferences. Experimenting with different timings can help you determine the method that works best for your training and recovery.

Cycling Off Creatine: A Thoughtful Strategy for Long-Term Gains

Cycling off creatine is a strategy some athletes utilise to reset muscle sensitivity and potentially enhance long-term strength gains. While no strict guidelines dictate how frequently to cycle off, many individuals choose to take breaks after several months of continuous use.

The rationale behind cycling off is that prolonged use may lead to diminishing returns. By taking a break, you may restore your body’s natural sensitivity to creatine, potentially resulting in improved effectiveness upon reintroduction.

During a cycling phase, it is essential to maintain workout intensity to prevent any loss of strength gains. Consider using this period to focus on alternative training methods or recovery strategies.

Ultimately, the decision to cycle off creatine should be based on personal preferences and individual responses. Monitoring your body’s reactions can help refine your supplementation strategy for optimal strength outcomes.

Potential Side Effects and Safety Considerations When Using Creatine

While creatine is generally regarded as safe for most individuals, it is critical to understand the potential side effects and safety considerations associated with supplementation.

Managing Gastrointestinal Issues Linked to Creatine Use

Some users may encounter gastrointestinal discomfort when taking creatine, particularly during the loading phase. Symptoms can include bloating, cramping, and diarrhoea, which can detract from the positive effects of supplementation.

To alleviate these challenges, opting for a form of creatine with enhanced solubility, such as creatine HCL, may be beneficial. Additionally, taking smaller doses throughout the day rather than one large dose can aid digestion.

It is essential to pay attention to your body’s reactions. If you experience persistent gastrointestinal issues with one type of creatine, consider switching to a different formulation or reducing your dosage. Finding the right creatine for your body can optimise benefits while minimising discomfort.

While some discomfort may be expected, severe or prolonged issues should prompt a discussion with a healthcare professional. Understanding your body’s responses enables you to navigate supplementation safely.

Evaluating Kidney Health Concerns Related to Creatine Supplementation

Concerns regarding the potential impact of creatine on kidney function have surfaced, particularly among individuals with pre-existing kidney conditions. While research indicates that creatine is safe for healthy individuals, those with kidney issues should approach supplementation with caution and consult a healthcare provider beforehand.

For healthy athletes, maintaining adequate hydration is crucial while taking creatine. Ensuring sufficient water intake can support kidney function and mitigate any potential stress caused by increased creatine levels.

Monitoring your body’s response to creatine is vital, as is being vigilant for any changes in your health. Regular check-ups and blood tests can provide valuable insights into your kidney function and overall health status while using creatine.

Always consider your unique circumstances when deciding to incorporate creatine supplementation into your routine, prioritising your health and safety above all else.

Prioritising Hydration to Prevent Muscle Cramps When Using Creatine

Maintaining sufficient water intake is crucial when using creatine, as it helps to prevent dehydration and muscle cramps. Creatine draws water into muscle cells, which can heighten the risk of dehydration if you’re not consuming enough fluids.

To reduce the likelihood of cramping, aim to stay well-hydrated throughout your training sessions. Monitoring urine colour can serve as a quick gauge of your hydration status; a pale yellow colour indicates good hydration, while a dark yellow colour suggests a need for increased fluid intake.

Incorporating electrolytes may also assist in balancing hydration levels and diminishing the risk of cramping. Athletes engaging in intense training or prolonged workouts should be particularly mindful of their fluid intake to ensure optimal performance.

By prioritising hydration and being attentive to your body’s signals, you can safely enjoy the benefits of premium creatine supplements for strength without the risk of dehydration or cramping.

Maximise Your Results by Combining Creatine with Other Effective Supplements

Creatine is highly effective on its own, but its benefits can be amplified when combined with other supplements. Here’s how you can optimise your strength training through strategic supplementation.

Enhance Recovery and Growth with Synergistic Protein Powders

Combining creatine with protein powders can significantly bolster muscle recovery and growth. Protein is vital for muscle repair and synthesis, while creatine provides the energy necessary for high-intensity workouts. The synergy between these two supplements can result in superior overall strength gains.

Many athletes choose to consume a post-workout protein shake that includes creatine, facilitating immediate recovery and muscle support. This combination creates a powerful recovery strategy, effectively harnessing the advantages of both supplements.

Moreover, creatine can enhance the effectiveness of protein by promoting protein synthesis, ensuring that your muscles receive the essential nutrients required for recovery and growth. This makes it an ideal strategy for anyone seeking to maximise their strength training outcomes.

When combining creatine with protein, consider the timing of your intake to ensure optimal benefits. Consuming both supplements post-workout can create a potent recovery window that promotes muscle growth and strength improvements.

Common Queries about Creatine Supplements

What are the primary advantages of creatine for strength training?

Creatine enhances muscle growth, boosts performance, accelerates recovery, increases power output, and improves hydration, all contributing to more effective strength training.

How should I take creatine for the best results?

A common approach is to begin with a loading phase of 20 grams per day for approximately a week, followed by a maintenance dose of 3-5 grams per day. Timing around workouts can also enhance effectiveness.

Is creatine safe for use?

For most healthy individuals, creatine is safe when used as directed. However, those with pre-existing kidney conditions should consult a healthcare professional before commencing supplementation.

Can I experience side effects from using creatine?

Some users may encounter gastrointestinal discomfort, cramping, or dehydration if not adequately hydrated. Monitoring your intake and selecting the appropriate form can help mitigate these issues.

Should I consider cycling off creatine?

Cycling off creatine can assist in resetting muscle sensitivity, but it’s not essential for everyone. Consider your individual needs and responses when deciding whether to cycle off.

Can I combine creatine with other supplements?

Yes, creatine can be effectively paired with protein powders and other supplements to enhance recovery and performance. Combining it with protein after a workout can yield significant benefits.

How long does it take to see results from creatine supplementation?

Many users report noticeable improvements in strength and performance within a week, especially when utilising a loading phase. Individual outcomes may vary based on factors such as workout intensity and diet.

What is the best type of creatine for achieving strength gains?

Creatine monohydrate is the most researched and widely used form, recognised for its effectiveness. However, creatine HCL and buffered creatine can also offer benefits based on individual preferences.

Can creatine be beneficial for endurance training?

While creatine is primarily associated with strength training, it can also enhance performance in high-intensity interval training and sports that require short bursts of energy.

How much water should I consume while taking creatine?

It is generally recommended to increase fluid intake while using creatine, aiming for at least 2-3 litres of water daily to ensure proper hydration and support kidney function.

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